7 Best CBD Oil For Pain
Helps you relieve pain and inflammation

Cannabidiol (CBD) is a viable alternative treatment for various health problems, particularly anxiety, seizures, and pain relief.

CBD is among 113 cannabinoids found in the cannabis plant innately. CBD oils, lotions, tinctures, and gummies are just a few of the CBD oil products available, and they can potentially benefit those suffering from pain.

If you want to learn about CBD oil and pain management, read this guide until the end. We’ll look at how CBD oil helps with the pain.

What is CBD oil?

Cannabidiol-CBD is one of the starring compounds of the cannabis plant. CBD is a non-toxic cannabinoid that opens up a world of therapeutic benefits upon consumption.

Speaking of CBD oil, it contains a blend of carrier oil and CBD extract.

These carrier oils can vary from product to product; however, the most common CBD carrier oils are MCT or hemp seed oil.

Since CBD is extracted from the hemp plant, the spectrum of CBD also varies depending on the presence of other compounds of plants. there are three different varieties of CBD oil that are:

• Full-spectrum
• broad-spectrum
• CBD Isolate

Full-spectrum CBD contains all phytocannabinoids of the hemp plant, including THC (the toxic cannabinoid). The broad spectrum also has all the cannabinoids and terpenoids but THC. CBD Isolate does not have any other chemical with CBD making it best for people who want to enjoy only CBD effects.

It is worth mentioning that Cannabinoids are dissolvable in oil but not in water. CBD increases its bioavailability and shelf life, making it best for individuals.

Moreover, CBD oil also diffuses in many products such as gummies, coffee pods, tinctures, and lotions.

How does CBD oil work?

Cannabis is long hauled for pain management and inflammation as medical use.

Cannabis or hemp oil has been used for pain and inflammation for centuries. Not only medicinal uses, but CBD flower has also been utilized in various forms and for varied reasons for over 10,000 years. Clothing, ropes, paper, and boots are hemp-made products.

CBDs working for different health conditions does so by stimulating the endocannabinoid system (ECS). It is one of the body’s necessary functions to keep the internal working of organs in balance.

This cell signaling system is comprised of three main elements:

1. Endocannabinoid
2. Receptors
3. Enzymes

Endocannabinoids

Endocannabinoids are naturally occurring substances produced by the body. CBD and THC, two active chemicals in the cannabis plant, are remarkably similar to the endogenous cannabinoids that regulate your endocannabinoid system. To date, scientists have only discovered two important endocannabinoids:

• Anandamide (AEA)
• 2-arachidonoylglycerol (2-AG)

Endocannabinoid receptors

The cell signaling mechanism that communicates with endocannabinoids is called endocannabinoid receptors. It encourages the ECS to function after it is coupled to these receptors. These receptors, similar to endocannabinoids, are found all through the human body.

The following are the two most essential endocannabinoid receptors:

• CB1 receptors, present in the central nervous system
• CB2 receptors are present in the peripheral nervous system and immunological cells.

Many researchers believe that a third receptor is also present, albeit there is not enough evidence to prove it.

Enzymes

Enzymes are the ECS’s concluding elements, and their purpose is to decompose the endocannabinoids once they’ve completed their task.

There is two main key enzymes:

• Anandamide is broken down by the fatty acid amide hydrolase FAAH.
• The enzyme monoacylglycerol acid lipase decomposes 2-AG.

Working of ECS

You can consider receptors and cannabinoids as locks and keys. When you consume cannabinoids, they interact with ECS receptors present in your body and unlock them to signal the brain to action. Depending on the presence of ECS receptors in your body, that specific area will get benefits from cannabinoids.

Effects of ECS Stimulation

The ECS is complex, and scientists have still not figured out how it functions or what all of its possible roles are. The ECS has been connected to the following activities according to research:

• Appetite regulation and metabolic process
• Chronic discomforts and inflammations
• Immune responses
• Mood regulation
• Motor functions and memory
• Sleep regulation
• Heart functions
• Bone restoration and development
• Liver
• Anxiety disorders
• Skin and nerve function

Each of these activities helps to maintain equilibrium or balance your inner functions. Moreover, when an external factor, including such pain from an accident or a temperature, disrupts your body’s homeostasis, your ECS jumps in to assist your body in returning to its optimal state.

CBD oil to Relieve pain

Understanding CBD and its working in the human body is no small task which is why studying CBD is quite complex. The complexity of CBD is apparent from its interaction with numerous body receptors, neurons, and cells.

However, numerous researches are focusing on this holistic compound of the hemp plant, trying to know the working of CBD for different conditions.

To understand the working of CBD oil’s pain-relieving effects, let us consider a scenario. When you get bruised or injured, tissues in your surrounding area release substances that start a chain reaction of inflammatory responses and perceptual reactivity.

Simply put, these signals from tissues cause pain to be transmitted to the spinal cord via a series of neurotransmitters that run throughout the body.

The twist is added to these pain signals when they reach an entry point after going through the spine. These entry points work as a filter of signs, which stretches the brain for comprehension.

In other words, these gateways can parameterize the pain signal that reaches the brain. When many pain impulses are allowed to flow, the brain perceives tremendous suffering. If the stimulus is ceased at the gateway, the brain interprets reduced discomfort.

These gateways have guards in the form of opioid and vanilloid receptors.

While traditional pain medicines activate the opioid receptors, the vanilloid, which is a new sort of molecule, is stimulated by CBD. Whenever you have a burning sensation or muscle stiffness, your vanilloid receptors are not working fine as they are primarily responsible for controlling pain signals from burning and inflammatory disorders.

You’ve probably read a great deal on how CBD oil can help with chronic ailments like arthritis. This is attributable to the fact that CBD oil engages the vanilloid receptors, resulting in a reduction in chronic pain signal transmission to the brain related to illnesses such as arthritis, muscular injuries, and so on.

Not only does CBD stimulate the valliniod, but it also limits the pain and discomfort by solving the root cause of the pain since it is known to diminish body inflammation. Besides, CBD also assists in damage recovery thanks to its antioxidant properties.

Many athletes also consider CBD for their post-workout muscle stiffness because it diminishes muscle spasticity by relaxing muscle fibers.

Though CBD has been around for centuries for its pain-relieving properties, the research on CBD is still in its infancy. Researchers are trying hard to find its potential for Pain-relieving effects and possible side effects.

What are the Benefits of CBD Oil?

While CBD is long hailed for its anti-anxiety properties, some recent research also covered CBD hemp oil for pain relief.

Some of the CBD oil cannabidiol benefits for pain relief are:

CBD for chronic pain

The binding activity of cannabinoids and receptors triggers a variety of cell activities that impact sensory signal transduction pathways.

Anti-inflammatory and pain-relieving qualities of these responses contribute to the relief of chronic pain. This suggests that CBD oil works for pain and inflammation. Moreover, it also helps those who suffer from chronic pains, like fibromyalgia or severe back pain.

Another study investigated the benefits of CBD oil for pain in seven persons who had chronic pain following renal transplantation, per a limited 2018 report. 6 out of 7 individuals said CBD oil worked for pain relief since their pain had significantly lessened after consuming CBD. However, more significant CBD levels caused increased suffering for one of the subjects, while lesser CBD oil worked for pain management.

Furthermore, the CBD oils’ pain relief properties are shown from a 2018 review study.

The review evaluated all trials that took place from 1975 to 2018, and also the scientists investigated different kinds of pains:

• Cancer-related Pain
• Neuropathic Pain (Pain that affects the nerves)
• Fibromyalgia (widespread pain that spreads all through the body)

According to these trials, researchers determined that CBD oil was helpful in general pain treatment and had no toxicities.

CBD for arthritis pain relief

CBD has been studied extensively as a possible replacement for prescribed pain relievers frequently used to treat arthritic pain.

The ECS has been linked to the pathogenesis of osteoarthritis, a progressive neurodegenerative condition characterized by chronic pain and inflammation (4).

According to a study, CBD can help people with osteoarthritis by blocking an enzyme that causes inflammation and pain in the joints.

Another research indicated that topical CBD alleviated joint inflammation and pain in arthritic rodents in a 2016 study. However, the optimal levels of CBD were found to be between 6.2 and 62 milligrams per day, as per the scientists.

CBD is believed to help the lower intensity of pain associated with arthritis by addressing the root causes of suffering.

CBD for cancer treatment relief

The National Cancer Institute (NCI) has recommended CBD as a feasible option for reducing post-chemotherapy treatment side effects such as headache, vomiting, upset stomach, and a decreased appetite.

In a 2010 study on cancer patients, researchers administered mouth sprays of a THC-CBD mixture to the participants. They gave the opioids in combination with the THC-CBD extract, which delivered more efficacious pain alleviation than the analgesics on its own.

After this study, another similar conclusion also resurfaced from a 2013 study on THC-CBD oral sprays.

 CBD for Multiple Sclerosis (MS) Pain

Multiple sclerosis (MS) is a neurological disorder that leads to symptoms, such as problems with vision, limb mobility, sensation, and balance.

It’s a persistent disease that can cause substantial immobility in some instances, although it can also be mild. CBD, recognized for its oxidative and anti-inflammatory properties, can help MS sufferers with their pain and irritation complaints.

CBD administration lowered pain, exhaustion, irritation, anxiety, and muscle spasms in persons with MS, according to a 2018 systematic study, and enhanced movement. The authors concluded that CBD treatment for persons with MS might be beneficial.

A CBD intranasal spray, Sativex, was reported in a 2014 scientific study to benefit individuals with MS to decrease pain, spasms, and excessive incontinence.

CBD tends to boost the immune system in experimental animals, lowering the autoimmune response, which underlies MS diagnosis, according to two separate 2021 scientific studies.

However, many studies suggest that CBD oil works for anxiety and pain; these studies are small-scaled or animal subjects. Researchers must conduct large-scale human research to confirm that CBD oil can be an organic solution for pain.

Does CBD Have Any Side Effects?

CBD has no known side effects, and also most topical CBD treatments do not travel through the bloodstream.

Nevertheless, there are some probable adverse effects, like Fatigue, Gastrointestinal trouble, Changes in Appetite, and Weight Gain or loss.

Moreover, CBD potentially interferes with the following substances:

• Various over (OTC) medications
• Prescribed drugs
• Nutritional supplements

If any of your drugs or pills have a “grapefruit precaution,” take precautions since grapefruit and CBD interact with proteins involved in drug breakdown.

As per one research, CBD-rich cannabis solution raised the risk of liver damage in mice which means it does have potential to damage liver with excessive dosage. However, the researchers force-fed several mice with extremely massive quantities of CBD-rich cannabis oil.

How To Choose Best CBD Oil For Pain Relief—Buying Guide

The CBD market has been snowballing due to the increasing interest of individuals, so many companies are selling all sorts of CBD products to get their share from the market.

There are indeed many excellent CBD products on the horizon, but that also indicates that several black sheep are selling harmful or mislabeled products in the name of a holistic solution.

It is essential to weed out good CBD products from bad ones as a CBD consumer. Otherwise, you will get into problems using bad quality oil or CBD oil with toxic or destructive components.

Below are some of the essential points in the best quality CBD oil for pain.

The Hemp Source

The hemp source can contribute a lot to the high quality of CBD oil for pain. It is worth mentioning that the hemp plant accumulates all the goods and evil of a soil medium or air, which means if grown in lousy quality or contaminated soil, it will absorb toxic chemicals from the ground.

Not only bio accumulators, but hemp plants are also known to enrich and fertilize the soil they grow in, which is why hemp plants were used to fertilize the grounds after the Chernobyl atomic disaster.

It is essential to choose high-grade hemp sourced from the USA or Canada for CBD oil because of its bioaccumulation properties.

Bear in mind that many vendors opt for sourcing hemp from Asian countries rich in toxic chemicals. The USA hemp farms follow strict guidelines outlined by the legislative authorities to produce only high purity CBD oil. For this, we recommend going with the best sources for CBD oil in the USA and Canada.

Potency

After hemp source, CBD oil potency is another crucial factor to consider after hemp source when looking for the most effective CBD oil. For those who do not know, potency is a way to tell the CBD levels in the products. Moreover, they also let you understand how much CBD you will get in every ml.

It is best to go with the brand that offers CBD oil in different potencies since it will allow you to choose the best fit. The strength of CBD oil can also have a lot to do with the price tag and its therapeutic effects.

However, remember that getting the best CBD oil for pain does not mean you should go for more potency to get instant relief. Instead, some individuals find comfort even in low strengths, so we suggest starting low and slow.

Extraction Method

Since CBD is present in trichomes of the hemp plant extracting it from raw plants entails an extraction process. Several extraction methods pull out CBD and other cannabinoids from hemp; however, the best and safest way is CO2 extraction.

CO2 works as a solvent agent in this process where it alters from gas to liquid, from probing into the hemp plant and pulling CBD. After removing the cannabinoids, CO2 evaporates and leaves the oil behind.

Other extraction methods entail using other solvents such as ethanol or oil. However, these methods tend to leave impurities in the final product. For that, we recommend trusting the brand for the highest-quality CBD oil that is transparent about its extraction processes.

Third-Party Testing

Many CBD brands sell products with mislabeled information which can alter the desired results. However, there is a way to confirm the ingredients and labeling of the CBD products through third-party lab tests.

Third-party laboratories are independent bodies that unbiasedly check CBD potency and contaminants in the product. Many companies send their product sample for every batch to check for impurities or potencies.

Most organic NON-GMO CBD oils include comprehensive third-party lab findings that can be seen on the company’s website. We recommend asking for a lab result if it is not available; however, if a brand is reluctant to show the COA, then refrain from purchasing.

CBD Spectrum

Like said earlier, CBD comes in three different spectrums; choosing CBD oil based on a range of cannabinoids is yet another point to consider.

If you plan to get CBD oil with THC for Pain, getting full-spectrum CBD oil is best since it induces the entourage effect. For those who don’t know, the entourage effect is the synergy of all chemicals of cannabis that increase the overall CBD effect.

However, bringing a broad spectrum or CBD isolate is best for those who don’t want to get the THC since they do not have THC in their composition.

All in all, it is up to your preference whether you like the best full-spectrum CBD oil for pain or pure CBD oil for pain management.

CBD Oil or CBD Topicals: Which One is Most Effective for Pain?

Since they’re several CBD products available to gain therapeutic effects, that leaves you to confuse which one to use for pain relief; however, as far as CBD for pain relief is concerned, you might think that topical CBD products work better than CBD oil.

This assertion is not true since CBD balms and lotions can only work for shallow pains. CBD topical products such as balms, creams, and lotion only affect the bodily structure that is a centimeter or so deep under the skin.

Chronic pains such as muscle and joint inflammation are way more complicated which can not be tackled with topical application of CBD. On the other hand, CBD oil is best for chronic pain because it weeds out the root cause of the pain by maintaining the equilibrium of the body’s internal function through ECS.

Besides, CBD topical might need a more generous amount of cream over the pained area, costing you more than CBD oil.

Although, this does not imply that you ought to buy only CBD oil for pain, not topical products. Using CBD oil and topical can help you get the pain relieved instantly. Here you can find out if topical use of oral CBD oil is effective?

Conclusion: Buying CBD oil for pain relief

CBD is highly regarded for its analgesic properties and a good reason. While not inducing adverse side effects like prescribed medications, CBD can be the best holistic solution for pain-relieving.

Although there is not enough data to justify CBD or CBD oil as an ideal way for pain relief, experts suggest that these treatments have a big future.

CBD products may provide comfort for many patients suffering from acute pain without creating overdose or addiction.

Consult your doctor if you’re willing to try CBD for pain since a medical expert can better tell you how and what amount of CBD to take for pain relief.